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Kamila Castro Grokoski

Palestra: Perspectivas da Nutrição no Transtorno do Espestro Autista

Ontem foi dia de Palestra a convite da Equipe do Projeto Pana da Universidade Federal de Pelotas (UFPEL). Falar sobre as perspectivas da nutrição noTranstorno do Espectro Autista foi enriquecedor!

O estudo PANA (Protocolo de Atendimento Nutricional ao Autista) é vinculado a Faculdade de Nutrição e ao Programa de Pós-Graduação em Nutrição e Alimentos da UFPEL, atuando nas áreas de pesquisa e de assistência nutricional de crianças e adolescentes com diagnostico de TEA.


Conforme falado ontem na palestra, segue abaixo a lista completa de referências citadas durante a palestra.


Abraços, Kamila


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Yesterday was a Talk Day, invited by the Pana Study Team at the Federal University of Pelotas (UFPEL). Talking about the perspectives of nutrition in Spectrum Disorder was enriching!

The PANA study is associated to the Undergraduate Nutrition Course and the Graduate Program in Nutrition and Food at UFPEL, which operates in the areas of research and nutritional assistance to children and adolescents diagnosed with ASD.


As talked about yesterday in the lecture, below is the complete list of references cited during the talk.


With love, Kamila


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Referências / References:


Transtorno do Espectro Autista / Autism Spectrum Disorder:

Youth with Autism: Roundtable Views of Services Needed During the Transition into Adulthood - GAO-17-109. Link: https://www.gao.gov/products/gao-17-109


Miller, L. E., Dai, Y. G., Fein, D. A., & Robins, D. L. (2021). Characteristics of toddlers with early versus later diagnosis of autism spectrum disorder. Autism : the international journal of research and practice, 25(2), 416–428. https://doi.org/10.1177/1362361320959507.

Zwaigenbaum, L., Brian, J. A., & Ip, A. (2019). Early detection for autism spectrum disorder in young children. Paediatrics & child health, 24(7), 424–443. https://doi.org/10.1093/pch/pxz119.


Maenner, M. J., Shaw, K. A., Bakian, A. V., Bilder, D. A., Durkin, M. S., Esler, A., Furnier, S. M., Hallas, L., Hall-Lande, J., Hudson, A., Hughes, M. M., Patrick, M., Pierce, K., Poynter, J. N., Salinas, A., Shenouda, J., Vehorn, A., Warren, Z., Constantino, J. N., DiRienzo, M., … Cogswell, M. E. (2021). Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018. Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002), 70(11), 1–16. https://doi.org/10.15585/mmwr.ss7011a1.


Nutrição e neurodesenvolvimento / Nutritrion and neurodevelopment:

Cormack, B. E., Harding, J. E., Miller, S. P., & Bloomfield, F. H. (2019). The Influence of Early Nutrition on Brain Growth and Neurodevelopment in Extremely Preterm Babies: A Narrative Review. Nutrients, 11(9), 2029. https://doi.org/10.3390/nu11092029.


Fatores hormonais e endócrinos / Hormonal and endocrine factors:

LoParo, D., & Waldman, I. D. (2015). The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis. Molecular psychiatry, 20(5), 640–646. https://doi.org/10.1038/mp.2014.77.


Rutigliano, G., Rocchetti, M., Paloyelis, Y., Gilleen, J., Sardella, A., Cappucciati, M., Palombini, E., Dell'Osso, L., Caverzasi, E., Politi, P., McGuire, P., & Fusar-Poli, P. (2016). Peripheral oxytocin and vasopressin: Biomarkers of psychiatric disorders? A comprehensive systematic review and preliminary meta-analysis. Psychiatry research, 241, 207–220. https://doi.org/10.1016/j.psychres.2016.04.117.


Rajamani, K. T., Wagner, S., Grinevich, V., & Harony-Nicolas, H. (2018). Oxytocin as a Modulator of Synaptic Plasticity: Implications for Neurodevelopmental Disorders. Frontiers in synaptic neuroscience, 10, 17. https://doi.org/10.3389/fnsyn.2018.00017.


Crider, A., & Pillai, A. (2017). Estrogen Signaling as a Therapeutic Target in Neurodevelopmental Disorders. The Journal of pharmacology and experimental therapeutics, 360(1), 48–58. https://doi.org/10.1124/jpet.116.237412.


Greene, S. M., Sanchez, Y. R., Pathapati, N., Davis, G. N., & Gould, G. G. (2021). Assessment of autism-relevant behaviors in C57BKS/J leptin receptor deficient mice. Hormones and behavior, 129, 104919. https://doi.org/10.1016/j.yhbeh.2020.104919.


Valleau, J. C., & Sullivan, E. L. (2014). The impact of leptin on perinatal development and psychopathology. Journal of chemical neuroanatomy, 61-62, 221–232. https://doi.org/10.1016/j.jchemneu.2014.05.001.


Castro, K., Faccioli, S. L., Perry, I., Riesgo, S. R. (2019). Leptin and adiponectin correlations with body composition and lipid profile in children with Autism Spectrum Disorder.

bioRxiv 621003; doi: https://doi.org/10.1101/621003.


Camilleri M. (2015). Peripheral mechanisms in appetite regulation. Gastroenterology, 148(6), 1219–1233. https://doi.org/10.1053/j.gastro.2014.09.016.


Fatores imunológicos / Immunological factors:

Filiano, A., Xu, Y., Tustison, N. et al. Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature 535, 425–429 (2016). https://doi.org/10.1038/nature18626.


Meltzer, A., & Van de Water, J. (2017). The Role of the Immune System in Autism Spectrum Disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 42(1), 284–298. https://doi.org/10.1038/npp.2016.158.


Meyer U. (2019). Neurodevelopmental Resilience and Susceptibility to Maternal Immune Activation. Trends in neurosciences, 42(11), 793–806. https://doi.org/10.1016/j.tins.2019.08.001.


Fatores gastrointestinais / Gastrointestinal factors:

Madra, M., Ringel, R., & Margolis, K. G. (2020). Gastrointestinal Issues and Autism Spectrum Disorder. Child and adolescent psychiatric clinics of North America, 29(3), 501–513. https://doi.org/10.1016/j.chc.2020.02.005.


Holingue, C., Newill, C., Lee, L. C., Pasricha, P. J., & Daniele Fallin, M. (2018). Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence. Autism research : official journal of the International Society for Autism Research, 11(1), 24–36. https://doi.org/10.1002/aur.1854.


Fattorusso, A., Di Genova, L., Dell'Isola, G. B., Mencaroni, E., & Esposito, S. (2019). Autism Spectrum Disorders and the Gut Microbiota. Nutrients, 11(3), 521. https://doi.org/10.3390/nu11030521.


Ristori, M. V., Quagliariello, A., Reddel, S., Ianiro, G., Vicari, S., Gasbarrini, A., & Putignani, L. (2019). Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions. Nutrients, 11(11), 2812. https://doi.org/10.3390/nu11112812.


Krigsman, A., & Walker, S. J. (2021). Gastrointestinal disease in children with autism spectrum disorders: Etiology or consequence?. World journal of psychiatry, 11(9), 605–618. https://doi.org/10.5498/wjp.v11.i9.605.


Taniya, M. A., Chung, H. J., Al Mamun, A., Alam, S., Aziz, M. A., Emon, N. U., Islam, M. M., Hong, S. S., Podder, B. R., Ara Mimi, A., Aktar Suchi, S., & Xiao, J. (2022). Role of Gut Microbiome in Autism Spectrum Disorder and Its Therapeutic Regulation. Frontiers in cellular and infection microbiology, 12, 915701. https://doi.org/10.3389/fcimb.2022.915701.


Robertson, R. C., Manges, A. R., Finlay, B. B., & Prendergast, A. J. (2019). The Human Microbiome and Child Growth - First 1000 Days and Beyond. Trends in microbiology, 27(2), 131–147. https://doi.org/10.1016/j.tim.2018.09.008.


Estado nutricional + Consumo alimentar + Comportamento alimentar /

Nutritional status + Food consumption + Eating behavior:



Castro, K., Slongo Faccioli, L., Baronio, D., Gottfried, C., Schweigert Perry, I., & Riesgo, R. (2017). Body composition of patients with autism spectrum disorder through bioelectrical impedance. Nutricion hospitalaria, 34(4), 875–879. https://doi.org/10.20960/nh.210.


Dhaliwal, K. K., Orsso, C. E., Richard, C., Haqq, A. M., & Zwaigenbaum, L. (2019). Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder. International journal of molecular sciences, 20(13), 3285. https://doi.org/10.3390/ijms20133285.


Castro, K., Faccioli, L. S., Baronio, D., Gottfried, C., Perry, I. S., & Riesgo, R. (2016). Feeding behavior and dietary intake of male children and adolescents with autism spectrum disorder: A case-control study. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 53, 68–74. https://doi.org/10.1016/j.ijdevneu.2016.07.003.


Margari, L., Marzulli, L., Gabellone, A., & de Giambattista, C. (2020). Eating and Mealtime Behaviors in Patients with Autism Spectrum Disorder: Current Perspectives. Neuropsychiatric disease and treatment, 16, 2083–2102. https://doi.org/10.2147/NDT.S224779.


Marí-Bauset, S., Zazpe, I., Mari-Sanchis, A., Llopis-González, A., & Morales-Suárez-Varela, M. (2014). Food selectivity in autism spectrum disorders: a systematic review. Journal of child neurology, 29(11), 1554–1561. https://doi.org/10.1177/0883073813498821.


Castro, K., Perry, I. S., Ferreira, G. P., Marchezan, J., Becker, M., & Riesgo, R. (2019). Validation of the Brief Autism Mealtime Behavior Inventory (BAMBI) Questionnaire. Journal of autism and developmental disorders, 49(6), 2536–2544. https://doi.org/10.1007/s10803-019-04006-z.


Sharp, W. G., Berry, R. C., McCracken, C., Nuhu, N. N., Marvel, E., Saulnier, C. A., Klin, A., Jones, W., & Jaquess, D. L. (2013). Feeding problems and nutrient intake in children with autism spectrum disorders: a meta-analysis and comprehensive review of the literature. Journal of autism and developmental disorders, 43(9), 2159–2173. https://doi.org/10.1007/s10803-013-1771-5.





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